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Hotels in Santee

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Conveniently located off I-95 at Exit 98, we are less than four miles from Santee National Golf Course and Lake Marion Golf course. A variety of dining options are just a short five-minute ... Read more
The Hampton Inn Santee-I-95, SC hotel in South Carolina is located at I-95, Exit 98, and is a state-of-the-art, interior corridor hotel with two elevators. The hotel is in ... Read more
At the Best Western Plus Santee Inn you’re sure to find that little something extra. With our modern amenities and thoughtful design, the Best Western Plus Santee Inn will stand out among other hotels ... Read more

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9117 Old Number 6 Hwy, Santee, SC
The Holiday Inn Santee hotel is perfect for recreational activities. Just off I-95 in Santee, SC, our hotel's location is less than an hour from both Columbia and Charleston, two unique cities to ... Read more
114 Bradford Boulevard, Santee, SC